Regulatory Mechanisms Controlling Prothrombin and the Development of Blood Coagulation Factors During Gestation

作者: C. Thomas Kisker , David Bohlken , Stanley Perlman , Ann Louise Olson , Jean Robillard

DOI: 10.1007/978-4-431-65871-9_13

关键词:

摘要: Disorders of blood coagulation are common in newborn infants. Major hemorrhage or thrombosis was found 40% neonatal deaths one survey and intraventricular detected 26% 101 autopsies infants another [1,2]. Thus, problems related to and/or play a major role the mortality infants, particularly premature The relationship between increased risk for abnormalities is unclear. Decreased levels factor activities less easily defined because range normal greater than adult low number based upon standards present even full-term newborns. Furthermore, many factors (including prothrombin VII, IX, X) differ depending on gestational age infant with lowest

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