Ischaemic stroke in progressive systemic sclerosis.

摘要: Progressive systemic sclerosis (PSS) or scleroderma is a multisystem disease affecting the skin, lungs, myocardium, kidneys and gastrointestinal tract. Primary involvement of cerebral arteries in PSS has been reported but is very rare. A 61–year–old woman suffering from scleroderma for six years was hospitalised for two subsequent episodes transient acute dysarthria left hemiparesis. After five hours first onset symptoms, she was submitted to brain magnetic resonance (MR) protocol that showed right subinsular ischaemic lesion whole right middle artery (MCA) territory hypoperfusion. Intracranial epiaortic MR angiography reported focal stenosis M2 portion MCA. She immediately treated with i.v. high dose steroids oral acetylsalicylic acid. At one–month follow up, findings were confirmed. We have documented infarct PSS patient. In our opinion, stroke caused by a localised autoimmune angiopathy.