Current treatment approach to locally advanced esophageal cancer: is resection mandatory?

摘要: Ongoing controversy surrounds the question of whether locally advanced cancer esophagus should be resected or treated with nonsurgical methods. Survival after resection, particularly patients squamous cell cancer, remains poor. Results recent studies suggest that in cases there is no clear survival advantage favoring surgery, but local tumor control significantly improved resection. Besides this clinically relevant difference, important issues concerning design and conduct most have not been investigated carefully deserve critical discussion. Of particular note fact surgery has yet compared a approach treating adenocarcinoma esophagus. Consequently, standard approach, at least for subtype. Response to induction chemotherapy radiation will determine future treatment algorithms, promising tools predicting response are currently being investigated.