Evaluating the validity of an instrumental variable study of neuroleptics: can between-physician differences in prescribing patterns be used to estimate treatment effects?

作者: M Alan Brookhart , Jeremy A. Rassen , Philip S. Wang , Colin Dormuth , Helen Mogun

DOI: 10.1097/MLR.0B013E318070C057

关键词:

摘要: Background:Postmarketing studies of prescription drugs are challenging because prognostic variables that determine treatment choices often unmeasured. In this setting, instrumental variable (IV) methods exploit differences in prescribing patterns between physicians may be used to estimate t

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