The Suppression of Iron Release from Activated Myoglobin by Physiological Electron Donors and by Desferrioxamine
作者： C. Rice-Evans , G. Okunade , R. Khan
DOI: 10.3109/10715768909088161
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摘要: Interactions between ferrimyoglobin and hydrogen peroxide have been postulated to lead the formation of activated ferryl myoglobin. In such systems hydroxyl radical has also demonstrated by its ability degrade deoxyribose subsequent release iron from porphyrin ring We investigated potential for ferrylmyoglobin exposed peroxide; modulation stability haem group membranes in presence desferrioxamine ascorbate assessed. The results show that is suppressed membranes, apparently reduction myoglobin species, lipid peroxidation occurs. desferrioxamine, species electron donating properties trihydroxamate moiety, which functions as a chain-breaking ant...
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