Protective effect of Coccinia indica on changes in the fatty acid composition in streptozotocin induced diabetic rats.

摘要: The present study was undertaken to investigate the effect of Coccinia indica, an indigenous plant used in Ayurvedic Medicine India, on blood glucose, plasma insulin, cholesterol, triglycerides, free fatty acids and phospholipids acid composition total lipids liver, kidney brain normal streptozotocin (STZ) diabetic rats. Oral administration ethanolic extract indica leaves (200 mg/kg body weight, CLEt) for 45 days rats decreased concentrations acids, viz., palmitic, stearic, oleic whereas linolenic arachidonic insulin were elevated. These results suggest that CLEt exhibits hypoglycaemic hypolipidaemic effects STZ induced It also prevents changes produced during diabetes. at 200 weight better than glibenclamide.