Prevalence of diabetes and impaired glucose tolerance in elderly subjects and their association with obesity and family history of diabetes.

作者: L. Mykkanen , M. Laakso , M. Uusitupa , K. Pyorala

DOI: 10.2337/DIACARE.13.11.1099

关键词:

摘要: The goal of this study was to investigate the prevalence impaired glucose tolerance (IGT) and non-insulindependent diabetes mellitus (NIDDM) in elderly subjects their association with obesity, central a family history diabetes. A representative population sample 1300 (471 men, 829 women) aged 65–74 yr participated study. participation rate 71%. rates previously newly diagnosed NIDDM IGT, based on an oral test, were 8.7, 7.0, 17.8% men 11.7, 7.1, 19.1% women. Thus, 33.8% 37.9% women had abnormal according World Health Organization criteria. Obesity (body mass index ≥27 kg/m 2 ≥25 obesity (waist-hip ratio ≥0.98 ≥0.89 doubled IGT or NIDDM. combination associated more marked increase than Simultaneous presence threefold (65.4 vs. 24.1% 52.8 19.6% women, P

参考文章(28)
ELIZABETH BARRETT-CONNOR, THE PREVALENCE OF DIABETES MELLITUS IN AN ADULT COMMUNITY AS DETERMINED BY HISTORY OR FASTING HYPERGLYCEMIA American Journal of Epidemiology. ,vol. 111, pp. 705- 712 ,(1980) , 10.1093/OXFORDJOURNALS.AJE.A112948
R. J. Jarrett, H. Keen, J. H. Fuller, M. McCartney, Worsening to diabetes in men with impaired glucose tolerance (“borderline diabetes”) Diabetologia. ,vol. 16, pp. 25- 30 ,(1979) , 10.1007/BF00423146
H. Keen, R.J. Jarrett, P. McCartney, The ten-year follow-up of the Bedford survey (1962-1972): glucose tolerance and diabetes. Diabetologia. ,vol. 22, pp. 73- 78 ,(1982) , 10.1007/BF00254832
Jack H. Medalie, Major Factors in the Development of Diabetes Mellitus in 10,000 Men Archives of Internal Medicine. ,vol. 135, pp. 811- 817 ,(1975) , 10.1001/ARCHINTE.1975.00330060055007
E. Agner, B. Thorsteinsson, M. Erikson, Impaired Glucose Tolerance and Diabetes Mellitus in Elderly Subjects Diabetes Care. ,vol. 5, pp. 600- 604 ,(1982) , 10.2337/DIACARE.5.6.600
H. Keen, S. Ng Tang Fui, 1 The definition and classification of diabetes mellitus Clinics in Endocrinology and Metabolism. ,vol. 11, pp. 279- 305 ,(1982) , 10.1016/S0300-595X(82)80017-0
Patricia J. Coon, Eugene R. Bleecker, Donald T. Drinkwater, Deborah A. Meyers, Andrew P. Goldberg, Effects of body composition and exercise capacity on glucose tolerance, insulin, and lipoprotein lipids in healthy older men: A cross-sectional and longitudinal intervention study Metabolism. ,vol. 38, pp. 1201- 1209 ,(1989) , 10.1016/0026-0495(89)90160-1
Ahmed H. Kissebah, Alan N. Peiris, Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes \/ Metabolism Reviews. ,vol. 5, pp. 83- 109 ,(1989) , 10.1002/DMR.5610050202
L.-O. Ohlson, B. Larsson, P. Bj�rntorp, H. Eriksson, K. Sv�rdsudd, L. Welin, G. Tibblin, L. Wilhelmsen, Risk factors for type 2 (non-insulin-dependent) diabetes mellitus. Thirteen and one-half years of follow-up of the participants in a study of Swedish men born in 1913 Diabetologia. ,vol. 31, pp. 798- 805 ,(1988) , 10.1007/BF00277480
E. M. Damsgaard, O. K. Faber, A. Froland, A. Green, M. Hauge, N. V. Holm, S. Iversen, Prevalence of fasting hyperglycemia and known non-insulin-dependent diabetes mellitus classified by plasma C-peptide: Fredericia survey of subjects 60-74 yr old. Diabetes Care. ,vol. 10, pp. 26- 32 ,(1987) , 10.2337/DIACARE.10.1.26