Temps de doublement du PSA et son calcul

摘要: Prostate Specific Antigen (PSA) is currently the best marker for prostate cancer, although it not very specific this disease. The use of PSA kinetic, in addition to its absolute value, theoretically attractive a large number clinical situations. Based on review literature, authors report various methods used study with particular emphasis most reliable method: doubling time. After describing definitions and calculate parameter, discuss situations which could be useful: surveillance prostatic tumours after initial diagnosis high-risk patients or refusing treatment, prognostic factor before curative evaluation efficacy tumour aggressiveness at time biochemical recurrence treatment during endocrine therapy.