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摘要: In the war on cancer, a great deal of attention is being paid to knowing ‘enemy’. It widely believed that by understanding driving forces underlying researchers can develop better ways target disease. Currently, large-scale efforts have been under taken completely characterize molecular changes in common human cancers (http://cancergenome.nih.gov/) (Collins & Bearker, 2007). However, as more learned about debate increases what exactly enemy is: cells making up bulk tumour, rare tumour stem regrow microenvironment, subset cancer with metastatic potential, etc. Studies associated Neurofibromatosis type 1 (NF1) are helping define relationship between many these different cell types. still unclear how enemies related each other and they interact wage cancer's patient.