作者: Luis H. Ripoll , Joseph Triebwasser , Larry J. Siever
DOI: 10.1017/CBO9780511910395.015
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摘要: Patients with comorbid major depression and generalized anxiety disorder (GAD) tend to have a more severe prolonged course of illness greater functional impairment. GAD is one the most common mental disorders in primary medical-care settings, associated increased use health services. Current theories on pathological fit multifactorial epigenetic model that integrates early stressors, inherited acquired vulnerabilities, risks developing interrelated or coincidental somatic diseases. The tolerability profile prescribed medication an important consideration, particularly when long-term treatment recommended. Distressing symptoms stopping are many classes psychotropic drug, including selective serotonin reuptake inhibitor (SSRIs), serotonin-norepinephrine inhibitors (SNRIs), benzodiazepines. There clearly room for improvement development efficacious acceptable pharmacological approaches management this common, distressing, typically disabling, often persistent disorder.