Unterscheidung der Penicilloinsäuren von funktionellen Derivaten ihrer. α‐Carboxylgruppe mittels Penamaldat‐Stabilitätsbestimmung

摘要: The distinction between derivatives of penicilloic acids with modified α-carboxyl function and the corresponding themselves by means a photometric test is described. procedure involves conversion penicillin to penamaldates action mercuric chloride, comparison stability extinction at 282 nm in phosphate buffer pH 7,4. stabilities free made from are quite low (half life 4 5 minutes) contrast high penamaldoyl obtained α-derivatives acids. Some characteristics method discussed, its potential usefulness for quantitative analysis mixtures acid demonstrated.