Stroke: disappointing results for clazosentan in CONSCIOUS-2.

作者: Philip M. Meyers , E. Sander Connolly

DOI: 10.1038/NRNEUROL.2011.168

关键词:

摘要: Clazosentan—a drug previously demonstrated to reduce angiographic vasospasm in patients with aneurysmal subarachnoid hemorrhage—had no significant effect on vasospasm-related morbidity and mortality the CONSCIOUS-2 trial. A multifactorial cause for delayed ischemic neurological deficits might partly account these negative findings.

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