Prolonged Air Leak Following Radical Upper Lobectomy: An Analysis of Incidence and Possible Risk Factors

摘要: Study objectives To examine the incidence and clinical significance of prolonged air leak (PAL) in patients undergoing radical upper lobectomy to determine potential risk factors for PAL this group patients. Design Retrospective review a prospective database. Setting Experience one thoracic surgeon at tertiary care cancer center. Patients One hundred consecutive right mediastinal lymph node dissection non-small cell lung over an 11-year period. Measurements was defined as lasting >7 days. Preoperative, intraoperative, postoperative data were collected analyzed associated with PAL. Results most prevalent complication, comprising 25.5% all complications seen, average 12.1 ±5.3 In 21 26 PAL, complication only morbidity identified. There no statistically significant difference patient age, gender, preoperative FEV 1 diffusion carbon monoxide, exposure neoadjuvant chemotherapy, status pulmonary fissures, or pathologic stage between vs remaining 74 without complication. A significantly greater proportion had /FVC ratio ≤50% (6/26 5/74; p=0.02). longer median length hospital stay (11 7 days; p=0.0001). Moreover, single common reason extended hospitalization (21/58, 36% causes). Conclusion is alarmingly frequent cause lobectomy. Severe obstructive disease predisposes development