The association between gastric endoscopic findings and histologic premalignant lesions in the Iranian rural population.

作者: Ramin Niknam , Alireza Manafi , Mohammad Reza Fattahi , Laleh Mahmoudi

DOI: 10.1097/MD.0000000000000715

关键词:

摘要: Atrophic gastritis, intestinal metaplasia, and gastric dysplasia are histologic premalignant lesions (PMLs). Correlation between the endoscopic findings PMLs is not clear. This study was designed to determine possible association of PMLs. Over 28 months consecutive rural patients with dyspepsia were categorized into 3 groups: 1—normal, 2—ulcerative or without concurrent abnormality, 3—abnormal non-ulcerative. Biopsies antrum body taken from all included examined for presence PMLs. Any mucosal abnormality also biopsied. From 7340 evaluated patients, an overall 1973 included. 55.7% in group 1; 3.8% 2 40.5% 3. A within sex analysis showed that majority male subgroup (P < 0.001) likewise groups (P < 0.001). The prevalence significantly higher than 1 (P < 0:001) but difference significant (P = 0.484). Mean (±SD) age patient 50.25 ± 17.71 whereas 41.16 ± 16.48 (P < 0.001). This has abnormal findings, increased can be considered as risk factors formation Until further investigations we propose any on mucosa (ulcerative non-ulcerative) could biopsied evaluation probable especially old men.

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