The Artificial Gut Concept

摘要: In 1970 we first described a system for self-administration of intravenous nutrition in the home (1, 11). The concept an artificial gut arose as logical development following progress other fields medicine, particular, hemodialysis patients with end-stage renal disease, together improved techniques parenteral hospitalized patients. Initially, used methods access to circulation which had proved so successful on hemodialysis; i. e., arteriovenous shunts or fistulas. Unfortunately, requiring long-term have inadequate peripheral vessels and high incidence clotting limited usefulness both fistulas such cases. Consequently, were obliged design right atrial catheter incorporated certain features that made it suitable use our (2, 9), this device has been obtain majority Our program is now its sixth year, experience includes over 50 treated (HPN).