作者: Simon de Lusignan , Charalambos Sismanidis , Iain M Carey , Stephen DeWilde , Nicky Richards
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摘要: Type 2 diabetes is an important cause of morbidity and mortality. Its prevalence appears to be increasing. Guidelines exist regarding its management. Recommendations drug therapy have changed. Little known about the influence these guidelines changed recommendations on actual management patients with type diabetes. This study aims document trends in prevalence, treatment recording measures related diabetes; assess whether recommended targets can met. The population comprised subjects registered between 1994 2001 74 general practices England Wales which routinely contribute Doctors' Independent Network database. Approximately 500,000 10,000 diabetics were each year. rose from 17/1000 25/1000 2001. Drug has changed: use long acting sulphonylureas falling while that short sulphonylureas, metformin newer therapies including glitazones Electronic HbA1c, blood pressure, cholesterol weight risen steadily, improvements control pressure levels occurred. However, glycaemic not improved, obesity increased. percentage a BMI under 25 kg/m2 fell 27.0% 19.4% (p < 0.001). Prevalence primary care accordance best evidence. Monitoring but further improvement possible. Despite this, diabetic rising.