Sodium Acetate, Sodium Acid Pyrophosphate, and Citric Acid Impacts on Isolated Peripheral Lymphocyte Viability, Proliferation, and DNA Damage.
作者： Yasmina M. Abd-Elhakim , Abeer Anwar , Mohamed M. Hashem , Gihan G. Moustafa , Khaled Abo-El-Sooud
DOI: 10.1002/JBT.22171
关键词:
摘要: The present study examined the impacts of sodium acetate (SA), acid pyrophosphate (SAPP), and citric (CA) on viability, proliferation, DNA damage isolated lymphocytes in vitro. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) lactate dehydrogenase (LDH) release assays were adopted to evaluate cell while comet assay was employed assess genotoxic effects. cells incubated with different levels SA (50, 100, 200 mM), SAPP (25, 50, 100 mM/L), or CA (100, 200, 300 μg/mL). treated tested food additives showed concentration-dependent decreases both viability proliferation. A increase LDH also observed. results indicated that SA, SAPP, increased percentage, tail length, moment a manner. current are cytotoxic
sci-hub.se 参考文章(40)
L.A. Visconti, E.H.K. Yen, R.B. Johnson, Effects of sodium acetate on rat bone-nodule formation and mineralization in vitro Archives of Oral Biology. ,vol. 43, pp. 729- 733 ,(1998) , 10.1016/S0003-9969(98)00027-2
Ashraf Awad, Laila Y. AL-Ayadhi, Yasmina M. Abd-Elhakim, Samah R. Khalil, Combined Cytogenotoxic Effects of Bee Venom and Bleomycin on Rat Lymphocytes: An In Vitro Study BioMed Research International. ,vol. 2014, pp. 173903- 173903 ,(2014) , 10.1155/2014/173903
Rabia Sarıkaya, Şükran Çakır, Genotoxicity testing of four food preservatives and their combinations in the Drosophila wing spot test Environmental Toxicology and Pharmacology. ,vol. 20, pp. 424- 430 ,(2005) , 10.1016/J.ETAP.2005.05.002
Serkan Yılmaz, Fatma Ünal, Deniz Yüzbaşıoğlu, The in Vitro Genotoxicity of Benzoic Acid in Human Peripheral Blood Lymphocytes Cytotechnology. ,vol. 60, pp. 55- 61 ,(2009) , 10.1007/S10616-009-9214-Z
Ellen Bruzell Roll, Jon E. Dahl, Gry Runningen, Else Morisbak, In vitro cell death induced by irradiation and chemicals relevant for dental applications; dose-response and potentiation effects. European Journal of Oral Sciences. ,vol. 112, pp. 273- 279 ,(2004) , 10.1111/J.1600-0722.2004.00128.X
Takao Iino, Akira Manome, Sanae Okada, Tai Uchimura, Kazuo Komagata, Effects of sodium acetate on the production of stereoisomers of lactic acid by Lactobacillus sakei and other lactic acid bacteria. Journal of General and Applied Microbiology. ,vol. 47, pp. 223- 239 ,(2001) , 10.2323/JGAM.47.223
Yu F Sasaki, Satomi Kawaguchi, Asako Kamaya, Miyuki Ohshita, Kazumi Kabasawa, Kayoko Iwama, Kazuyuki Taniguchi, Shuji Tsuda, The comet assay with 8 mouse organs: results with 39 currently used food additives. Mutation Research-genetic Toxicology and Environmental Mutagenesis. ,vol. 519, pp. 103- 119 ,(2002) , 10.1016/S1383-5718(02)00128-6
Amit Prasad Amit Prasad, KN Prasad, Abhisek Yadav Abhisek Yadav, RK Gupta, Sunil Pradhan Sunil Pradhan, Sanjeev Jha Sanjeev Jha, Mukesh Tripathi Mukesh Tripathi, Mazhar Husain Mazhar Husain, Lymphocyte transformation test: a new method for diagnosis of neurocysticercosis. Diagnostic Microbiology and Infectious Disease. ,vol. 61, pp. 198- 202 ,(2008) , 10.1016/J.DIAGMICROBIO.2007.12.016
Himadri Pandey, Vikas Kumar, B.K. Roy, Assessment of genotoxicity of some common food preservatives using Allium cepa L. as a test plant Toxicology reports. ,vol. 1, pp. 300- 308 ,(2014) , 10.1016/J.TOXREP.2014.06.002
Prosper M’Bemba-Meka, Nicole Lemieux, Saroj K. Chakrabarti, Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro Chemico-Biological Interactions. ,vol. 156, pp. 69- 80 ,(2005) , 10.1016/J.CBI.2005.07.004