Hypocalcemia following thyroid surgery: incidence and risk factors. A longitudinal multicenter study comprising 2,631 patients

摘要: Postoperative hypocalcemia is the most frequent complication of total thyroidectomy. It may have a delayed onset, and therefore delays discharge from hospital, requiring calcium replacement therapy to alleviate clinical symptoms. During 7-month period, 2,631 consecutive patients undergoing primary or completion thyroidectomy were prospectively followed up underwent analysis regarding postoperative hypoparathyroidism. Data collected by questionnaires 39 Italian endocrine surgery units affiliated Endocrine Surgery Units Association (Club delle Unita di EndocrinoChirurgia-UEC), where thyroid routinely performed. The incidence hypoparathyroidism was 28.8 % (757 patients), including transient (27.9 %-734 patients) permanent (0.9 %-23 patients). rate asymptomatic 70.80 %. higher in symptomatic group (7.5 %) than one (1.5 %). Female experienced more frequently male (29.7 21.2 %, respectively; p < 0.0001). percentage developing which parathyroid glands intraoperatively identified preserved identification not achieved (29.2 vs. 18.7 0.01). This prospective study confirmed main risk factors for hypocalcemia: cancer, nodal dissection, female gender. farther showed that identifying parathyroids has an important role prevent though with hypocalcemia. A suitable informed consent should especially emphasize importance some increasing after surgery.