Scaffold-in-Scaffold Potential to Induce Growth and Differentiation of Cardiac Progenitor Cells.
作者： Matteo Ciocci , Federico Mochi , Felicia Carotenuto , Emilia Di Giovanni , Paolo Prosposito
关键词:
摘要: The design of reliable biocompatible and biodegradable scaffolds remains one the most important challenges for tissue engineering. In fact, properly designed must display an adequate interconnected porosity to facilitate cell spreading colonization inner layers, release physical signals concurring modulate function ultimately drive fate. this study, a combination optimal mechanical biochemical properties has been considered one-component three-dimensional (3D) multitextured hydrogel scaffold favor cell–scaffold interactions. A polyethylene glycol diacrylate woodpile (PEGDa-Wp) structure order 100 μm manufactured using microstereolithography process. Subsequently, PEGDa-Wp embedded in PEGDa obtain 3D scaffold-in-scaffold (3D-SS) system. Finally, 3D-SS capability address fate assessed human Lin− Sca-1+ cardiac progenitor cells (hCPCs). Results have shown ...
sci-hub.se 参考文章(41)
James S. Forrester, Anthony J. White, Satoshi Matsushita, Tarun Chakravarty, Raj R. Makkar, New Paradigms of Myocardial Regeneration Post-Infarction JACC: Cardiovascular Interventions. ,vol. 2, pp. 1- 8 ,(2009) , 10.1016/J.JCIN.2008.10.010
Jacques P. Guyette, Jonathan M. Charest, Robert W. Mills, Bernhard J. Jank, Philipp T. Moser, Sarah E. Gilpin, Joshua R. Gershlak, Tatsuya Okamoto, Gabriel Gonzalez, David J. Milan, Glenn R. Gaudette, Harald C. Ott, Bioengineering Human Myocardium on Native Extracellular Matrix Circulation Research. ,vol. 118, pp. 56- 72 ,(2016) , 10.1161/CIRCRESAHA.115.306874
Jonathan Leor, Yoram Amsalem, Smadar Cohen, Cells, scaffolds, and molecules for myocardial tissue engineering Pharmacology & Therapeutics. ,vol. 105, pp. 151- 163 ,(2005) , 10.1016/J.PHARMTHERA.2004.10.003
Preetha Anand, Sherin G. Thomas, Ajaikumar B. Kunnumakkara, Chitra Sundaram, Kuzhuvelil B. Harikumar, Bokyung Sung, Sheeja T. Tharakan, Krishna Misra, Indira K. Priyadarsini, Kallikat N. Rajasekharan, Bharat B. Aggarwal, Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochemical Pharmacology. ,vol. 76, pp. 1590- 1611 ,(2008) , 10.1016/J.BCP.2008.08.008
Zu-yong Wang, Erin Yiling Teo, Mark Seow Khoon Chong, Qin-yuan Zhang, Jing Lim, Zhi-yong Zhang, Ming-hui Hong, Eng-san Thian, Jerry Kok Yen Chan, Swee-Hin Teoh, None, Biomimetic Three-Dimensional Anisotropic Geometries by Uniaxial Stretch of Poly(ɛ-Caprolactone) Films for Mesenchymal Stem Cell Proliferation, Alignment, and Myogenic Differentiation Tissue Engineering Part C-methods. ,vol. 19, pp. 538- 549 ,(2013) , 10.1089/TEN.TEC.2012.0472
Matthias P. Lutolf, Penney M. Gilbert, Helen M. Blau, Designing materials to direct stem-cell fate Nature. ,vol. 462, pp. 433- 441 ,(2009) , 10.1038/NATURE08602
Giancarlo Forte, Marilena Minieri, Paolo Cossa, Daniele Antenucci, Marilena Sala, Viola Gnocchi, Roberta Fiaccavento, Felicia Carotenuto, Paolo De Vito, Patrizia Morena Baldini, Maria Prat, Paolo Di Nardo, Hepatocyte Growth Factor Effects on Mesenchymal Stem Cells: Proliferation, Migration, and Differentiation Stem Cells. ,vol. 24, pp. 23- 33 ,(2006) , 10.1634/STEMCELLS.2004-0176
Matthew T. Wolf, Christopher L. Dearth, Sonya B. Sonnenberg, Elizabeth G. Loboa, Stephen F. Badylak, Naturally derived and synthetic scaffolds for skeletal muscle reconstruction. Advanced Drug Delivery Reviews. ,vol. 84, pp. 208- 221 ,(2015) , 10.1016/J.ADDR.2014.08.011
Jason J. Gajarsa, Robert A. Kloner, Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities. Heart Failure Reviews. ,vol. 16, pp. 13- 21 ,(2011) , 10.1007/S10741-010-9181-7
Samuel E. Senyo, Yevgeniya E. Koshman, Brenda Russell, Stimulus interval, rate and direction differentially regulate phosphorylation for mechanotransduction in neonatal cardiac myocytes FEBS Letters. ,vol. 581, pp. 4241- 4247 ,(2007) , 10.1016/J.FEBSLET.2007.07.070