Antibiotic sensitivity of bacteria associated with community-acquired urinary tract infection in Britain

摘要: Twelve laboratories in different parts of Britain each supplied approximately 80 consecutive urinary bacterial isolates from community patients. All strains were identified by a central laboratory, where sensitivity to variety orally administered antimicrobials was determined microtitre broth dilution. 65.1% Escherichia coil, 23.4% 'coliforms' other than E. 4.6% Proteus and Morganella spp., 1.8% Pseudomonas 2.4% enterococci, 0.7% group B streptococci, 1.5% coagulase-negative staphylococci 0.5% Staphylococcus aureus. Using previously published breakpoint values, 98.9% all found be sensitive norfloxacin ciprofloxacin, 95.7% co-amoxiclav, 86.8% nitrofurantoin, 77.4% cephalexin, 75.6% trimethoprim, 75.0% cephradine 51.7% amoxycillin. There some differences sensitivities between centres, particularly those the cephalosporins. standard breakpoints, submitting overestimate nitrofurantoin underestimate quinolones co-amoxiclav; there considerable overestimation