The participation of trimethylammonium in the mouse erythrocyte epitope recognized by monoclonal autoantibodies.
作者： Dan Serban , Jaqueline M. Pages , Alain E. Bussard , Isaac P. Witz
DOI: 10.1016/0165-2478(81)90012-2
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摘要: Abstract Monoclonal IgM anti-erythrocyte autoantibody produced by a NZB-derived hybridoma has been found to react with trimethylammonium-containing compounds. Such compounds are able prevent the lysis of bromelain-treated mouse erythrocytes (BrMRBC) those autoantibodies. Using column insolubilized betaine hydrazide (BH) monoclonal antibody specifically retained. Elution this was accomplished 0.15 M choline (Ch).
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