Corneal stroma demarcation line after standard and high-intensity collagen crosslinking determined with anterior segment optical coherence tomography.
作者： George D. Kymionis , Konstantinos I. Tsoulnaras , Michael A. Grentzelos , Argyro D. Plaka , Dimitrios G. Mikropoulos
DOI: 10.1016/J.JCRS.2013.10.029
关键词:
摘要: Purpose To use anterior segment optical coherence tomography (AS-OCT) to compare corneal stroma demarcation line depth after collagen crosslinking (CXL) with 2 treatment protocols. Setting Vardinoyiannion Eye Institute of Crete, Faculty Medicine, University Heraklion, Greece. Design Prospective comparative interventional case series. Methods Corneal was performed in all eyes using the same ultraviolet-A (UVA) irradiation device (CCL-365). Eyes were treated for 30 minutes 3 mW/cm according standard Dresden protocol (Group 1) or 10 minutes 9 mW/cm UVA intensity 2). One month postoperatively, independent observers measured AS-OCT. Results Sixteen patients (21 eyes) enrolled. Group 1 comprised 7 (9 and 2, 9 (12 eyes). The mean 350.78 μm ± 49.34 (SD) (range 256.5 410 μm) 288.46 ± 42.37 μm 238.5 353.5 μm) 2; statistically significantly deeper than ( P =.0058, t test unpaired data). Conclusion a 30-minute CXL 10-minute procedure high-intensity irradiation. Financial Disclosure No author has financial proprietary interest any material method mentioned.
cardiff.ac.uk 参考文章(8)
Cosimo Mazzotta, Angelo Balestrazzi, Claudio Traversi, Stefano Baiocchi, Tomaso Caporossi, Cristina Tommasi, Aldo Caporossi, Treatment of Progressive Keratoconus by Riboflavin-UVA-Induced Cross-Linking of Corneal Collagen: Ultrastructural Analysis by Heidelberg Retinal Tomograph II In Vivo Confocal Microscopy in Humans Cornea. ,vol. 26, pp. 390- 397 ,(2007) , 10.1097/ICO.0B013E318030DF5A
Theo Seiler, Farhad Hafezi, Corneal cross -linking -induced stromal demarcation line Cornea. ,vol. 25, pp. 1057- 1059 ,(2006) , 10.1097/01.ICO.0000225720.38748.58
Muriël Doors, Nayyirih G. Tahzib, Fred A. Eggink, Tos T.J.M. Berendschot, Carroll A.B. Webers, Rudy M.M.A. Nuijts, Use of Anterior Segment Optical Coherence Tomography to Study Corneal Changes After Collagen Cross-linking American Journal of Ophthalmology. ,vol. 148, pp. 844- 851 ,(2009) , 10.1016/J.AJO.2009.06.031
Jörg Krumeich, Jan Daniel, Lebend-Epikeratophakie und Tiefe Lamelläre Keratoplastik zur Stadiengerechten chirurgischen Behandlung des Keratokonus (KK) I-III Klinische Monatsblatter Fur Augenheilkunde. ,vol. 211, pp. 94- 100 ,(1997) , 10.1055/S-2008-1035103
Jason C.S. Yam, Clement W.N. Chan, Arthur C.K. Cheng, Corneal collagen cross-linking demarcation line depth assessed by Visante OCT After CXL for keratoconus and corneal ectasia. Journal of Refractive Surgery. ,vol. 28, pp. 475- 481 ,(2012) , 10.3928/1081597X-20120615-03
George D. Kymionis, Michael A. Grentzelos, Argyro D. Plaka, Nela Stojanovic, Konstantinos I. Tsoulnaras, Dimitrios G. Mikropoulos, Konstantinos I. Rallis, Vardhaman P. Kankariya, Evaluation of the corneal collagen cross-linking demarcation line profile using anterior segment optical coherence tomography. Cornea. ,vol. 32, pp. 907- 910 ,(2013) , 10.1097/ICO.0B013E31828733EA
Gregor Wollensak, Eberhard Spoerl, Theo Seiler, Riboflavin/ultraviolet-a–induced collagen crosslinking for the treatment of keratoconus American Journal of Ophthalmology. ,vol. 135, pp. 620- 627 ,(2003) , 10.1016/S0002-9394(02)02220-1
George D. Kymionis, Michael A. Grentzelos, George A. Kounis, Vasilios F. Diakonis, Aliki N. Limnopoulou, Sophia I. Panagopoulou, Combined transepithelial phototherapeutic keratectomy and corneal collagen cross-linking for progressive keratoconus. Ophthalmology. ,vol. 119, pp. 1777- 1784 ,(2012) , 10.1016/J.OPHTHA.2012.03.038