作者: Zi-Sheng Chen , Fang Yang , Huibo Ling , Mengxue Li , Jin-Ming Gao
DOI: 10.1021/ACS.ORGLETT.6B02813
关键词:
摘要: An efficient two component cycloaddition reaction to synthesize various substituted quinoline derivatives was developed. Ynone 1 functionalizated by N-oxide attacking the C3-oxetium site and C3-site regioselectively give 3 4. Analogues 3k 4v have a high binding constant with Hg2+ in CH3CN.