The Surface Ultrastructure of Normal and Leukemic Rat Lymphocytes

摘要: The surface ultrastructure of normal and leukemic rat lymphocytes has been compared by electron microscopy. Large small lymphocytes, both neoplastic, from blood lymph nodes, all showed a similar fine structure consisting unevenly distributed particles 100–300 A in diameter. Large cells, presumably reticulum with 1000 craters on their surface, were observed preparations except those the circulating rat. Shaking experiments indicated that intercellular adhesiveness these “crater cells” was greater than other cells nodes. In cell system used, low neoplastic cells. failure to observe difference suggests change state is not necessarily accompanied an alteration surface—at least lymphocytes. Of examined, only difference; also adhesiveness. This may be directly related