Méningite et confusion fébrile à rechute : encéphalite limbique révélant une maladie d’Hodgkin

作者: J. Serratrice , A. Ben Amri , R. Bouabdallah , M. Ceccaldi , P.-J. Weiller

DOI: 10.1016/J.NEUROL.2008.08.007

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摘要: Resume Introduction Nous rapportons une observation d’encephalite limbique associee a maladie d’Hodgkin. La presentation clinique etait marquee par evolution rechutes faite d’episodes eloignes de fievre et troubles cognitifs avec meningites recidivantes, curables le traitement la Elle est comparee rares cas litterature. A cette occasion sont rappelees les conceptions actuelles des encephalites limbiques separant notamment formes antigenes intracellulaires (paraneoplasiques mauvais pronostic), antigene membranaire (canalopathies potassiques, anticorps antineuropiles) sensibles l’immunotherapie bon pronostic sans anticorps. Observation Un homme, âge 75 ans, fut hospitalise pour l’exploration d’une confusion febrile rechute. En effet, il avait presente dans quatre annees precedant sa venue episodes spontanement regressifs febrile. Une meningite documentee plusieurs reprises. L’exploration ces phenomenes permit mettre en evidence encephalite paraneoplasique decouvrir l’aide imagerie emission positon d’Hodgkin sous-jacente. Le derniere regression complete durable tous symptomes. Conclusion Il justifie rechercher proliferations lymphomateuses etiologie nette. pathogenie dysimmune actuellement proposee rendrait compte association.

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