Conosilane A, an Unprecedented Sesquiterpene from the Cultures of Basidiomycete Conocybe siliginea

作者: Xiao-Yan Yang , Tao Feng , Zheng-Hui Li , Yu Sheng , Xia Yin

DOI: 10.1021/OL302468A

关键词:

摘要: Conosilane A (1), a novel sesquiterpene with an unprecedented carbon skeleton, was isolated from the cultures of basidiomycete Conocybe siliginea. Its structure elucidated by extensive spectroscopic methods, and absolute configuration determined single crystal X-ray diffraction analysis. found to inhibit 11β-hydroxysteroid dehydrogenase significantly.

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