Malaria Prophylaxis in Different Age Groups.

作者: Marie-Louise Mittelholzer , Michael Wall , Robert Steffen , Dieter Stürchler

DOI: 10.1111/J.1708-8305.1996.TB00750.X

关键词:

摘要: Background: There is a perceived increased health risk in senior visitors to malaria endemic countries. Methods: The authors sought compare effectiveness and tolerability of chemoprophylaxis travelers (≥60 years) with those younger (20–59 years). “Malpro 2” database consists more than 100,000 questionnaires completed by on charter planes returning from East Africa Europe during July 1988-December 1991. Among them, 9106 (9.1%) the were 60 years or older, 84,562 (84.6%) reported be 20–59 years. Variables demography, travel data, compared two subgroups. Results: Malaria was 8 (1/1000) elderly 189 (2.2/1000) aged Adjusting for age, sex, prophylaxis, duration stay logistic regression model, significantly frequent (p<.05). Any travel-associated illness 7.0% age group 13.6% rates who indicated they had “side effects” attributable prophylaxis varied between 9.7% 15.5% (p<.05). Conclusion: Senior tolerate visits tropics at least as well travelers.

参考文章(3)
Robert Steffen, Elisabeth Fuchs, Janine Schildknecht, M Funk, P Schlagenhauf, P Phillips-Howard, CG Nevill, U Naef, D Sturchler, Mefloquine compared with other malaria chemoprophylactic regimens in tourists visiting East Africa The Lancet. ,vol. 341, pp. 1299- 1303 ,(1993) , 10.1016/0140-6736(93)90814-W
C. G. Swift, Pharmacokinetics and prescribing in the elderly Journal of Antimicrobial Chemotherapy. ,vol. 34, pp. 25- 32 ,(1994) , 10.1093/JAC/34.SUPPL_A.25
Clas Ahlm, Sonia Lundberg, Kerstin Fessé, Johan Wiström, Health Problems and Self-medication among Swedish Travellers Scandinavian Journal of Infectious Diseases. ,vol. 26, pp. 711- 717 ,(1994) , 10.3109/00365549409008640