Sexual differentiation of synaptic connectivity and neuronal plasma membrane in the arcuate nucleus of the rat hypothalamus.
作者： J. Pe´rez , F. Naftolin , L.M. Garci´a Segura
DOI: 10.1016/0006-8993(90)91068-R
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摘要: Abstract Plasma membranes of the hypothalamic arcuate neurons rat show a sexually dimorphic phenotype: numerical density intramembrane protein particles is greater in females. Male and female Sprague-Dawley rats, 10, 20 100 days old, were studied order to determine whether sexual differentiation neuronal plasma membrane soma associated with establishment sex differences pattern axo-somatic synaptic contacts. Axo-somatic synapses counted thin sections nucleus assessed freeze-fracture replicas membrane. The number per length perikaryal increased from day 10 both sexes, reaching by values similar those found on 100. A difference synnapses was observed only 20-day-oldand 100-day old rats: females showed presynaptic inputs than males (P
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