Development and Application of Low-Modulus Biomedical Titanium Alloy Ti2448

摘要: Economic development leads to improved living standard, but is also attended by the following consequences: increased number of senile people who, due degenerative diseases such as arthritis, may need medical assistance in maintaining their convenience mobility, volume transportation terms cars and associated traffic accidents, amount leisure time channeled sports that have a higher than average risk injuries. All these require orthopaedic surgeries cause consumption biomedical materials. Load bearing orthopedic implants must satisfy requirements (Wang, 1996; Long & Rack, 1999): First all they are ideally without cytotoxicity, this places stringent restriction choice alloying elements. Secondly, long service life coupled with variety human activity demands excellence mechanical properties, primarily high strength fatigue resistance, low elastic modulus. This big challenge because for crystalline materials modulus tend increase or decrease simultaneously. Thirdly, wear resistance important causes not only implant loosening harmful reactions if debris deposited tissue. Finally, biochemical compatibility requires implanted possess superior corrosion body environment be bioactive. The first two aspects clearly fall into domain alloy design; last two, though closely related type composition, normally subjects surface modification. Judging from above titanium alloys stand out best class combination acceptable biocompatibility good properties strength, density, relatively excellent resistance. While Ti–6Al–4V used earliest engineering still benchmark among (Froimson et al., 2007), it was purpose-designed. In vanadium toxic both elemental state form oxide (Wapner, 1991; Eisenbarth 2004), there exits some correlation between V Al ions released long-term health problems Alzheimer disease, neuropathy ostemomalacia (Nag 2005). These facts highlight importance careful additions when designing new specifically use. main effect an on bone relates stress shielding, i.e., reduction vivo introduction implant. needed cells around thus shielded do survive. change 10