作者: Hans Jürgen Maier
DOI:
关键词:
摘要: A bi-phasic pharmaceutical composition for oral administration including one or more solid active ingredient containing particles dispersed within a semi-solid carrier formulation. The include coating with pH-triggered drug release properties and the formulation is formulated at pH that different than which of are triggered. Also described delivery system above dispenser pouch formed from flexible laminate sheets. Further, process manufacturing two-phase filling into pouches, allows patient to squeeze dispense contents package directly cavity.