作者: Ana Alfaro-Acha , Soham Al Snih , Mukaila A. Raji , Kyriakos S. Markides , Kenneth J. Ottenbacher
DOI: 10.1111/J.1532-5415.2007.01039.X
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摘要: OBJECTIVES: To examine the association between 8-foot time walk and change in cognitive function over older Mexican Americans. DESIGN: Data used are from Hispanic Established Population for Epidemiological Study of Elderly (1993–2001). SETTING: Five southwestern states: Texas, New Mexico, Colorado, Arizona, California. PARTICIPANTS: Two thousand seventy noninstitutionalized Mexican-American men women aged 65 who had a Mini-Mental State Examination (MMSE) score 21 or greater at baseline. MEASUREMENTS: Sociodemographic factors (age, sex, education, marital status), MMSE score, time, body mass index, medical conditions (stroke, heart attack, diabetes mellitus, depression, hypertension), near distant visual impairment. RESULTS: Using general linear mixed models, it was found that subjects with slowest significantly rate decline 7 years than fastest time. There significant time–by-time interaction scores. Subjects lowest quartile (estimate=−0.32, SE=0.08; P<.001) those highest quartile. This remained statistically after controlling potential confounding factors. CONCLUSION: Slow adults without impairment baseline an independent predictor 7-year period. may be early marker predementia state benefit early-intervention programs to prevent slow decline.