Basic principles in hyperthermic tumor therapy.

摘要: The first report of heat being useful in cancer treatment is by Busch (1866), who noted the disappearance a sarcoma after high fever caused erysipelas. Bruns (1887) reviewed all cases tumor regression reported literature. Coley (1893) injected patients with bacterial toxins deliberately to cause fever. There are many reports early 1900s use applied hyperthermia treating cancer. Interest declined during 1930s, due part advent antibacterial agents; consequently, number studies diminished. was then period renewed interest hyperthermia, for example, possibility combining X-rays, but because application technically difficult and therapeutic results megavoltage radiotherapy photons electrons were excellent, disappeared again as agent.