Prophylactic and/or therapeutic agent for NAFLD/NASH

作者: Jimma Fumie , Kagawa Tomohiro , Yamaoka Ippei , Soma Hiroyuki , Adachi Masakazu

DOI:

关键词:

摘要: A prophylactic and/or therapeutic agent for non-alcoholic fatty liver disease (NAFLD), in particular steatohepatitis (NASH), said comprising a concentrate of Japanese plum (Prunus mume) juice or processed product thereof. The agent, which is obtained with the use ingredients contained plant thereof, has high safety and can be easily taken. It was confirmed that hepatic fibrosis ameliorated by orally administering thereof to streptozocin (STZ)-induced NAFLD model mice STZ-induced NASH mice.

参考文章(12)
Hee Sun Yun, Yun Seok Choe, Won Jun Hwang, Hyung Joo Suh, Jin Man Kim, Kyung Mi Kim, Ki Won Kim, Sang Wook Ahn, Il Jun Kang, Young Chun Choi, Method for selectively inhibiting reuptake of serotonin and norepinephrine using yeast extract ,(2005)
Zhaolian Bian, Xiong Ma, Liver Fibrogenesis in Non-Alcoholic Steatohepatitis Frontiers in Physiology. ,vol. 3, pp. 248- 248 ,(2012) , 10.3389/FPHYS.2012.00248
Atsushi Hokari, Tomohisa Ishikawa, Hisao Tajiri, Takahide Matsuda, Osamu Ishii, Nobuyuki Matsumoto, Chiaki Okuse, Hideaki Takahashi, Takeshi Kurihara, Ko-ichi Kawahara, Ikuro Maruyama, Mikio Zeniya, Efficacy of MK615 for the treatment of patients with liver disorders World Journal of Gastroenterology. ,vol. 18, pp. 4118- 4126 ,(2012) , 10.3748/WJG.V18.I31.4118
Kenichi Ikejima, Sumio Watanabe, [Topics update in NAFLD: from bench side to clinics]. The Japanese journal of gastro-enterology. ,vol. 111, pp. 4- 13 ,(2014)
立志 大澤, 和久 大坂, 敏信 水田, 太郎 足立, Toshinobu Mizuta, 正一 足立, Taro Adachi, Kazuhisa Osaka, Shoichi Adachi, Tateshi Osawa, Food and drink for autophagy inducing action ,(2005)
和久 大坂, 太郎 足立, Takahide Matsuda, 正一 足立, Taro Adachi, Kazuhisa Osaka, Shoichi Adachi, 毅 栗原, Mikio Zenitani, Satoshi Nagashima, Atsushi Kusunoki, Muneharu Ikeda, 宗晴 池田, 聰 長嶋, 幹男 銭谷, 隆秀 松田, Takeshi Kurihara, Liver function improving agent for viral hepatitis patient ,(2010)