Quality of Life in Clinical Trials and Practice

摘要: Since 1948, when the World Health Organisation defined health as being not only absence of disease and infirmity but also presence physical, mental, social well-being, quality-of-life issues have become steadily more important in health-care practice researchl. There has been a nearly exponential increase use evaluation technique clinical research since 1973, five articles listed quality life reference key word Medline database. During subsequent 5-year periods there were 195, 273, 490, 1252 such articles2. Quality is increasingly incorporated into trials complementary endpoint to traditional outcomes mortality morbidity. Several factors are related growing interest life: advances medical care made available an array therapeutic options, with difference treatment choice. Quality-of-life becoming central chronic conditions that accompany growth ageing population.