Willingness to volunteer in future preventive HIV vaccine trials: issues and perspectives from three U.S. communities.

摘要: UNLABELLED This study examined perceived risks, benefits, and desired information related to willingness volunteer in preventive HIV vaccine trials. SAMPLE Purposive sampling was used select 90 participants among injecting drug users (Philadelphia, PA, U.S.A.); gay men (San Francisco, CA, black Americans (Durham, NC, U.S.A.). METHODS A qualitative interview guide elicited relating trial participation. Themes were developed from the transcribed texts freelists. RESULTS Stated a similar across three communities. Eight benefits reported, including self-benefits, altruism, stopping spread of AIDS. Seven risks negative side effects safety issues, contracting vaccine, social stigmatization. Participants voiced desire for eight types about issues trust confidentiality research process, health complications later assistance, methodology. CONCLUSIONS In this study, many as well participation cited. Scientists conducting trials need address community perceptions provide if enrollment is be diverse successful.