Amino Acid Receptors in CNS. I. GABA and Glycine in Spinal Cord
作者： Ronald W. Ryall
DOI: 10.1007/978-1-4684-3174-2_3
关键词:
摘要: Attempts to prove the identity of amino acid inhibitory transmitters in mammalian central nervous system received fresh impetus when Florey (1954) extracted an substance, factor I, from brain and subsequently (Bazemore et al., 1957) showed that it contained γ-aminobutyric (GABA). However, some active preparations I do not contain GABA (McLennan, 1958). In earliest studies (Honour McLennan, 1960; was found a topical application exposed spinal cord did reduce monosynaptic reflexes even though effects were observed with I. This seemed dampen enthusiasm for as transmitter somewhat, but later by other workers higher concentrations effective.
springer.com
sci-hub.se 参考文章(133)
M. KUNO, A. MUNEOKA, Further studies on site of action of systemic omega-amino acids in the spinal cord. Japanese Journal of Physiology. ,vol. 12, pp. 397- 410 ,(1962) , 10.2170/JJPHYSIOL.12.397
M J Neal, J M Hopkin, Thr release of 14C-glycine from electrically stimulated rat spinal cord slices. British Journal of Pharmacology. ,vol. 40, ,(1970)
L. Ho¨sli, E. Ho¨sli, P.F. Andre`s, Nervous tissue culture — a model to study action and uptake of putative neurotransmitters such as amino acids Brain Research. ,vol. 62, pp. 597- 602 ,(1973) , 10.1016/0006-8993(73)90727-0
J. W. Phillis, The pharmacology of synapses Pergamon Press. ,(1970)
Ulf Söderberg, Sten Skoglund, Curt von Euler, Structure and function of inhibitory neuronal mechanisms Pergamon Press. ,(1968)
D.R. Curtis, The pharmacology of spinal postsynaptic inhibition. Progress in Brain Research. ,vol. 31, pp. 171- 189 ,(1969) , 10.1016/S0079-6123(08)63237-9
Robert F. Schmidt, Presynaptic inhibition in the vertebrate central nervous system. Ergebnisse der Physiologie, biologischen Chemie und experimentellen Pharmakologie. ,vol. 63, pp. 20- 101 ,(1971) , 10.1007/BFB0047741
William C. De Groat, THE ACTIONS OF γ-AMINOBTJTYRIC ACID AND RELATED AMINO ACIDS ON MAMMALIAN AUTONOMIC GANGLIA Journal of Pharmacology and Experimental Therapeutics. ,vol. 172, pp. 384- 396 ,(1970)
Collins Gg, Drug-induced changes in the electrically evoked release of 3H- -aminobutyric acid (3H-GABA) from spinal cord. British Journal of Pharmacology. ,vol. 47, ,(1973)
Z Gottesfeld, J S Kelly, F Schon, Uptake of -aminobutyric acid (GABA) by sensory root ganglia. British Journal of Pharmacology. ,vol. 47, ,(1973)