RNA interference. An approach to produce knockout organisms and cell lines

作者: V. V. Kuznetsov

DOI: 10.1023/A:1026346325933

关键词:

摘要: In various eucaryotic organisms double-stranded RNA causes effective degradation of homologous mRNA molecules by a process called interference. interference is phenomenon associated with gene suppression via regulatory molecules, which are common in plants, animals, and fungi. The discovery stimulated the development new approaches for target expression, production stable knockout cell lines organisms, also studies on possible intracellular functions this phenomenon.

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