Digoxin concentrations in postmortem human tissues.

摘要: An extraction procedure is described that allows the application of a commercially available enzyme-multiplied immunoassay technique to measurement digoxin in whole blood, liver, and kidney. The concentrations were measured tissues obtained at autopsy from five patients who had been taking therapeutic doses prior death. Blood found be higher than range, perhaps due postmortem redistribution. Liver showed positive correlation with blood concentrations; this was not for kidney drug.