Nanoemulsions as potential vehicles for transdermal and dermal delivery of hydrophobic compounds: an overview.

作者: Faiyaz Shakeel , Sheikh Shafiq , Nazrul Haq , Fars K Alanazi , Ibrahim A Alsarra

DOI: 10.1517/17425247.2012.696605

关键词:

摘要: Introduction: In recent years, nanoemulsions have been investigated as potential drug delivery vehicles for transdermal and dermal of many compounds especially hydrophobic in order to avoid clinical adverse effects associated with oral the same compounds. Droplet size surface properties play an important role biological behavior formulation. Areas covered: this review, current literature both vitro well vivo has summarized analyzed. Expert opinion: Nanoemulsions formulated using a variety pharmaceutically acceptable excipients. cases nanoemulsions, skin irritation or toxicity issues on human beings not considered which needs be evaluated properly. last decade, much attention made exploring new types nanoemulsion-based system del...

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