The Opposing Effects of Hedonic and Eudaimonic Happiness on Gene Expression is Correlated Noise

摘要: Background. This paper re-analyzes the gene set data from Fredrickson et al. (2013) and (2015) which purportedly showed opposing effects of hedonic eudaimonic happiness on expression levels a genes that have been correlated with social adversity. Methods. Four non-parametric methods were used to test two null hypotheses addressed in original studies (H0 : Hedonia = 0 H0 Eudaimonia 0) as well hypothesis no difference effect between − 0). Results. Standardized (mean partial regression coefficients) are very small both 2013 2015 data, combined data. The p-values all four tests similar magnitude fail reject any models. Discussion. results unambiguously support effects, or detectable effect, pattern expression. apparently replicated is simply noise due geometry multiple given strongly measures happiness.