Retrospective observation of mycobacterium avium complex lung disease followed without treatment

摘要: BACKGROUND Although mild case of Mycobacterium avium complex (MAC) lung disease is often followed without treatment, the consensus appropriate time to start its treatment has not been established. AIM The aim study was evaluate characteristics patients with MAC who were withheld or delayed treatment. METHOD Data on for at least 6 months after diagnosis retrospectively reviewed. Changes in baseline and plain chest radiograph compared between untreated treated groups. To radiological findings, area each patient divided into zones. Each zone scored reference presence four elements as nodules, infiltration, cavity, bronchiectasis scores summed up. RESULTS Fifty-six investigated, including 15 initiated during observation. mean follow-up period 7.5 ± 5.8 years. There no significant differences groups, while initial image score (nodulues, ectasis) significantly higher group group. infiltration ectasis dramatically increased starting treatment; however, didn’t improve scores. On other hand, slowly but observation CONCLUSION Radiological findings may be useful predict progressive deterioration requiring