Mitomycin C and vinblastine in the treatment of advanced breast cancer

作者: J.A. Radford , R.K. Knight , R.D. Rubens

DOI: 10.1016/0277-5379(85)90241-X

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摘要: Forty-nine women with progressive metastatic breast cancer, extensively pretreated, received mitomycin C 12 mg/m2 and vinblastine 6 intravenously every 3 weeks. Eleven patients responded, giving a response frequency of 22%. Considering only the 40 evaluable after two or more courses treatment, is 27.5%. Responses occurred predominantly at soft tissue sites. Subjective toxicity was mild.

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