作者: Mikael Svedendahl , Si Chen , Mikael Käll , None
DOI: 10.1007/978-1-4614-3933-2_1
关键词:
摘要: This chapter introduces the basics of plasmon-based refractometric sensing, its application in label-free biomolecular analysis, and discusses differences between propagating plasmons localized terms refractive index sensitivity, sensing volume measurement methodology. Based on some recent nanoplasmonic studies, we discuss plasmon–substrate interactions possibility to perform long-range sensing. We also an experimental comparison particle-based thin film plasmonic biosensing, describe a method enhance sensitivity towards single molecule limit using enzymatic signal amplification.