Wound healing processes in cell cultures.

作者: Ju.M. Vasiliev , I.M. Gelfand , L.V. Domnina , R.I. Rappoport

DOI: 10.1016/0014-4827(69)90296-1

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摘要: Abstract Reactions of various types normal and neoplastic cell cultures to the mechanical removal a part culture were studied. 1. Normal cells actively migrated from edge wound on cell-free glass. Usually this migration was limited: most migrating remained within certain zone near edge. 2. Cells that synthetized or did not synthetize DNA before operation into in proportions similar their other parts culture. 3. Migration inhibited by colcemide. 4. Most induced begin synthesis after latent period about 12–18 h. This activation local: operated activated. 5. very slow as compared with cells. followed

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