Central Control of Feeding Behavior by the Secretin, PACAP, and Glucagon Family of Peptides

作者: Revathi Sekar , Lei Wang , Billy Kwok Chong Chow

DOI: 10.3389/FENDO.2017.00018

关键词:

摘要: Constituting a group of structurally related brain-gut peptides, secretin, PACAP and glucagon family peptide hormones exert their functions via interactions with the class B1 G protein-coupled receptors (GPCRs). In recent years, roles these peptides in neuroendocrine control feeding behavior have been specific area research focus for development potential therapeutic drug targets to combat obesity metabolic disorders. As result, some members analogues already utilized as agents clinical application. This review aims provide an overview current understanding on important role behavior.

参考文章(213)
Gunnar Sørensen, India A. Reddy, Pia Weikop, Devon L. Graham, Gregg D. Stanwood, Gitta Wortwein, Aurelio Galli, Anders Fink-Jensen, The glucagon-like peptide 1 (GLP-1) receptor agonist exendin-4 reduces cocaine self-administration in mice Physiology & Behavior. ,vol. 149, pp. 262- 268 ,(2015) , 10.1016/J.PHYSBEH.2015.06.013
Tetsuya Tachibana, Sachiyo Kubo, Md. Sakirul Islam Khan, Keiko Masuda, Kazuyoshi Ukena, Yajun Wang, Peripheral Injection of Chicken Growth Hormone-Releasing Hormone Inhibits Feeding Behavior in Chicks Journal of Poultry Science. ,vol. 53, pp. 29- 33 ,(2015) , 10.2141/JPSA.0150087
Ian P.Y. Lam, Francis K.Y. Siu, Jessica Y.S. Chu, Billy K.C. Chow, Multiple Actions of Secretin in the Human Body International Review of Cytology-a Survey of Cell Biology. ,vol. 265, pp. 159- 190 ,(2008) , 10.1016/S0074-7696(07)65004-9
Kimberly P. Kinzig, David A. D'Alessio, James P. Herman, Randall R. Sakai, Torsten P. Vahl, Helmer F. Figueiredo, Erin K. Murphy, Randy J. Seeley, CNS Glucagon-Like Peptide-1 Receptors Mediate Endocrine and Anxiety Responses to Interoceptive and Psychogenic Stressors The Journal of Neuroscience. ,vol. 23, pp. 6163- 6170 ,(2003) , 10.1523/JNEUROSCI.23-15-06163.2003
Peter Kristensen, Martin E. Judge, Lars Thim, Ulla Ribel, Kennet N. Christjansen, Birgitte S. Wulff, Jes T. Clausen, Per B. Jensen, Ole D. Madsen, Niels Vrang, Philip J. Larsen, Sven Hastrup, Hypothalamic CART is a new anorectic peptide regulated by leptin Nature. ,vol. 393, pp. 72- 76 ,(1998) , 10.1038/29993
Alyssa M. A. Toda, Richard L. Huganir, Regulation of AMPA receptor phosphorylation by the neuropeptide PACAP38 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 112, pp. 6712- 6717 ,(2015) , 10.1073/PNAS.1507229112
P Suchankova, J Yan, M L Schwandt, B L Stangl, E C Caparelli, R Momenan, E Jerlhag, J A Engel, C A Hodgkinson, M Egli, M F Lopez, H C Becker, D Goldman, M Heilig, V A Ramchandani, L Leggio, The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. Translational Psychiatry. ,vol. 5, ,(2015) , 10.1038/TP.2015.68
Sebastian GB Furness, Denise Wootten, Arthur Christopoulos, Patrick M Sexton, Consequences of splice variation on Secretin family G protein-coupled receptor function. British Journal of Pharmacology. ,vol. 166, pp. 98- 109 ,(2012) , 10.1111/J.1476-5381.2011.01571.X
Mads Tang-Christensen, Philip Just Larsen, Jesper Thulesen, John Rømer, Niels Vrang, The proglucagon-derived peptide, glucagon-like peptide-2, is a neurotransmitter involved in the regulation of food intake Nature Medicine. ,vol. 6, pp. 802- 807 ,(2000) , 10.1038/77535
Yumiko Mizuno, Kunikazu Kondo, Yasuhiro Terashima, Hiroshi Arima, Takashi Murase, Yutaka Oiso, Anorectic Effect of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) in Rats: Lack of Evidence for Involvement of Hypothalamic Neuropeptide Gene Expression Journal of Neuroendocrinology. ,vol. 10, pp. 611- 616 ,(2002) , 10.1046/J.1365-2826.1998.00244.X