Adjuvant Therapy for Residual Disease in Children With Medulloblastoma

作者: H. J. G. Bloom

DOI: 10.1007/978-3-642-81332-0_62

关键词:

摘要: It has been widely recognised for many years that postoperative radiotherapy is essential the eradication of medulloblastoma. Residual tumor leading to recurrence and early death inevitable following surgery alone. To achieve maximum number cures, must be meticulously planned carried out, ensuring coverage entire cerebro-spinal contents with dose in posterior fossa where most frequently seen [9]. also become clear only real chance cure depends upon first treatment: experience shown once occurs, any further treatment essentially palliative a fatal outcome practically certain. In spite these observations, established principles medulloblastoma are not universally applied very poor results still being some centres.

参考文章(27)
C.H. Chang, Hyperbaric oxygen and radiation therapy in the management of glioblastoma. National Cancer Institute monograph. ,vol. 46, pp. 163- ,(1977)
John Mealey, Peter V. Hall, Medulloblastoma in children. Survival and treatment. Journal of Neurosurgery. ,vol. 46, pp. 56- 64 ,(1977) , 10.3171/JNS.1977.46.1.0056
Robert M. Sutherland, Selective Chemotherapy of Noncycling Cells in an in Vitro Tumor Model Cancer Research. ,vol. 34, pp. 3501- 3503 ,(1974)
G.E. Adams, J.C. Asquith, D.L. Dewey, J.L. Foster, B.D. Michael, R.L. Willson, Electron Affinic Sensitization International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. ,vol. 19, pp. 575- 585 ,(1971) , 10.1080/09553007114550751
Harold J. Hoffman, E. Bruce Hendrick, Robin P. Humphreys, Metastasis via ventriculoperitoneal shunt in patients with medulloblastoma Journal of Neurosurgery. ,vol. 44, pp. 562- 566 ,(1976) , 10.3171/JNS.1976.44.5.0562
Takao Hoshino, Keiji Sano, Radiosensitization of Malignant Brain Tumours with Bromouridine (Thymidine Analogue) Acta Radiologica: Therapy, Physics, Biology. ,vol. 8, pp. 15- 26 ,(1969) , 10.3109/02841866909134433
Jack F. Fowler, Gerald E. Adams, Juliana Denekamp, Radiosensitizers of hypoxic cells in solid tumours Cancer Treatment Reviews. ,vol. 3, pp. 227- 256 ,(1976) , 10.1016/S0305-7372(76)80012-6
RG Parker, HC Berry, AJ Gerdes, MD Soronen, CM Shaw, Fast neutron beam radiotherapy of glioblastoma multiforme American Journal of Roentgenology. ,vol. 127, pp. 331- 335 ,(1976) , 10.2214/AJR.127.2.331
J L Foster, P J Conroy, A J Searle, R L Willson, Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells British Journal of Cancer. ,vol. 33, pp. 485- 490 ,(1976) , 10.1038/BJC.1976.78