Advances in pancreatic cancer detection.
作者： Cristiana Pistol Tanase , Monica Neagu , Radu Albulescu , Mihail Eugen Hinescu
DOI: 10.1016/S0065-2423(10)51006-0
关键词:
摘要: Pancreatic cancer represents a major challenge for research studies and clinical management. No specific tumor marker the diagnosis of pancreatic exists. Therefore, extensive genomic, transcriptomic, proteomic are being developed to identify candidate markers use in high-throughput systems capable large cohort screening. Understandably, complex pathophysiology requires sensitive biomarkers that can improve both early therapeutic monitoring. The lack single diagnostic makes it likely only panel is providing appropriate combination high sensitivity specificity. Biomarker discovery using novel technology prognostic upgrading pinpoint new molecular targets innovative therapy.
sci-hub.se 参考文章(208)
Lisa H Cazares, Jose I Diaz, Rick R Drake, O John Semmes, MALDI/SELDI protein profiling of serum for the identification of cancer biomarkers. Methods of Molecular Biology. ,vol. 428, pp. 125- 140 ,(2008) , 10.1007/978-1-59745-117-8_7
Jian-Guo Qiao, Expression of Survivin in pancreatic cancer and its correlation to expression of Bcl-2. World Journal of Gastroenterology. ,vol. 10, pp. 2759- 2761 ,(2004) , 10.3748/WJG.V10.I18.2759
Kevin F. Staveley-O'Carroll, Eric T. Kimchi, John J. Liang, Dongfeng Tan, Diagnostic and prognostic biomarkers in pancreatic carcinoma International Journal of Clinical and Experimental Pathology. ,vol. 2, pp. 1- 10 ,(2009)
Justice R, Johnson, Pazdur R, Sridhara R, Senderowicz Am, Zimmerman P, Erlotinib/Gemcitabine for First-Line Treatment of Locally Advanced or Metastatic Adenocarcinoma of the Pancreas Oncology. ,vol. 21, pp. 1696- 1706 ,(2007)
Michel M. Ouellette, Hong Jin Kim, Angela L. Groehler, Vladimir Khazak, Channing J. Der, Paul M. Campbell, Kwang M. Lee, Ras-driven transformation of human nestin-positive pancreatic epithelial cells. Methods in Enzymology. ,vol. 439, pp. 451- 465 ,(2008) , 10.1016/S0076-6879(07)00431-4
Nobuyuki Ohike, Toshio Morohoshi, Kyoko Kashima, Manabu Takahashi, Seishiro Mukai, Masashi Sato, Expression of the tumor suppressor gene maspin and its significance in intraductal papillary mucinous neoplasms of the pancreas. Hepatobiliary & Pancreatic Diseases International. ,vol. 7, pp. 86- 90 ,(2008)
Yu-Pei Zhao, Xiao Long, Quan Liao, Li-Jun Li, Shao-Mei Han, Ying-Chi Yang, Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head. Hepatobiliary & Pancreatic Diseases International. ,vol. 6, pp. 641- 645 ,(2007)
Andreas-Claudius Hoffmann, Ryutaro Mori, Daniel Vallbohmer, Jan Brabender, Ellen Klein, Uta Drebber, Stephan E. Baldus, Janine Cooc, Mizutomo Azuma, Ralf Metzger, Arnulf H. Hoelscher, Kathleen D. Danenberg, Klaus L Prenzel, Peter V. Danenberg, High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF. Neoplasia. ,vol. 10, pp. 674- 679 ,(2008) , 10.1593/NEO.08292
Fumihide Itokawa, Atsushi Sofuni, Toshio Kurihara, Kazuhiko Kasuya, Takayoshi Tsuchiya, Akihiko Tsuchida, Takao Itoi, Kazuto Nakamura, Kazuo Takei, Fuminori Moriyasu, Immunohistochemical analysis of p53 and MIB-1 in tissue specimens obtained from endoscopic ultrasonography-guided fine needle aspiration biopsy for the diagnosis of solid pancreatic masses Oncology Reports. ,vol. 13, pp. 229- 234 ,(2005) , 10.3892/OR.13.2.229
Claudia Gramigni, Graziella Bellone, Isabella Chiappino, Anna Novarino, Giorgio Emanuelli, Oscar Bertetto, Alfredo Addeo, Elena Tonel, Anna Carbone, Circulating vascular endothelial growth factor and interferon-gamma-inducible protein-10 levels in pancreatic cancer during chemotherapy. Anticancer Research. ,vol. 25, pp. 3287- 3291 ,(2005)