Diet, menopause and the risk of ovarian, endometrial and breast cancer.

摘要: Menopause, the permanent cessation of menstrual cycle, marks end a woman's reproductive lifespan. In addition to changes in sex hormone levels associated with menopause, its timing is another predictor future health outcomes such as duration presence vasomotor symptoms (VMS) and risk hormone-related cancers. With ageing population, it estimated that worldwide 1·2 billion women will be menopausal by year 2030. Previously effects factors (e.g. parity, age at menarche, pregnancy) socio-demographic on intermediate long-term menopause have been widely documented. However, little known about whether diet could an impact these. Therefore, we review current evidence associations VMS cancers ovarian, endometrial breast cancer. Dietary influence lifespan ovaries sex-hormones levels, hence natural menopause. Few studies reported association between diet, particular soya consumption, reduced VMS. Sustained oestrogen exposure has higher thus high-fat meat diets linked increased these better understand mechanistic pathways involved make stronger conclusions for relationships, further investigating dietary intakes patterns are required.