Prophylaxis of oropharyngeal candidiasis with clotrimazole.

作者: E Yeo , T Alvarado , V Fainstein , G P Bodey

DOI: 10.1200/JCO.1985.3.12.1668

关键词:

摘要: A total of 202 evaluable cancer patients were randomly assigned to receive or not oral clotrimazole as antifungal prophylaxis during hospitalization. Oropharyngeal candidiasis occurred in 1% the former and 27% latter (P less than .00001). Candida sp cultured from initial throat specimens 53 control 55 who received prophylaxis. subsequently developed 2% 38% = Oral is an effective agent for oropharyngeal susceptible patients.

参考文章(8)
Francoise Meunier-Carpentier, Timothy E. Kiehn, Donald Armstrong, Fungemia in the immunocompromised host: Changing patterns, antigenemia, high mortality The American Journal of Medicine. ,vol. 71, pp. 363- 370 ,(1981) , 10.1016/0002-9343(81)90162-5
Norma J. Owens, Prophylaxis of Oral Candidiasis With Clotrimazole Troches Archives of Internal Medicine. ,vol. 144, pp. 290- 293 ,(1984) , 10.1001/ARCHINTE.1984.00350140096014
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
Boh-Seng Yap, Oropharyngeal Candidiasis Treated With a Troche Form of Clotrimazole Archives of Internal Medicine. ,vol. 139, pp. 656- 657 ,(1979) , 10.1001/ARCHINTE.1979.03630430036012
F. Meunier-Carpentier, M. Cruciani, J. Klastersky, Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients European Journal of Cancer and Clinical Oncology. ,vol. 19, pp. 43- 48 ,(1983) , 10.1016/0277-5379(83)90396-6
F Meunier-Carpentier, Chemoprophylaxis of fungal infections The American Journal of Medicine. ,vol. 76, pp. 652- 656 ,(1984) , 10.1016/0002-9343(84)90290-0