作者: Christopher S. Simpson , William A. Ghali , Anthony J. Sanfilippo , Sabine Moritz , Hoshiar Abdollah
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摘要: Abstract Purpose The role of digoxin and verapamil in the control ventricular response rapid atrial fibrillation is well established. This study investigates how clonidine compares with these standard therapies rate for new-onset fibrillation. We set out to test hypothesis that effectively reduces heart patients Subjects Methods Forty were seen emergency department (≤24 hours' duration), stable, Eligible randomized receive either clonidine, digoxin, or verapamil. Changes blood pressure over 6 hours, as frequency conversion sinus rhythm recorded analyzed. Results mean reduction hours was 44.4 beats/min (95% confidence interval [CI] 28.4-60.4 beats/min) group, 52.1 CI 40.8-63.4 41.8 22.5-61.0 group. Analysis variance changes 3 groups after not significant ( P =.55). At 7 12 patients, 8 15 13 remained =.962 on χ 2 ). Conclusion Clonidine controls an efficacy comparable agents. (Am Heart J 2001;142:e3.)